Bangladesh is both an agricultural and energy deficient country. Sweet potatoes (Ipomoea batatus L.) are easy to grow and have a lot of starch, so they can be used to make fuel ethanol. This study looks at how to get the best amount of ethanol from sweet potatoes grown in Bangladesh. First, 100 grams of boiled sweet potato were mixed with 300 mL of clean water and then made germ-free. Two enzymes, 1750 units of α-amylase and 2000 units of glucoamylase, worked best to break down the starch. Then, 200 mL of yeast (Saccharomyces cerevisiae CCD) with a cell count of 1x10⁵ cells/mL was added to reach a total of 500 mL for fermentation. The results concluded that the optimized parameters are incubation time 6 days, pH 6.0, temperature 35◦C, sugar concentration 20 % (w/v) and inoculum concentration 10% v/v. Supplementation of external nitrogen sources (only sweet potato, urea, (NH4)H2PO4, only peptone and all nutrients) on ethanol production were also investigated. Many things affect how much ethanol is made. The final amount, 116.33 mL per liter with 35% purity, depends on getting the best conditions during the process.